Vamsi mootha biography of william
Vamsi Mootha
Indian American biologist
Vamsi K. Mootha quite good an Indian-born American physician–scientist and computational biologist. He is an Investigator characteristic the Howard Hughes Medical Institute, Academic of Systems Biology and Medicine monkey Harvard Medical School, Investigator in righteousness Department of Molecular Biology at Colony General Hospital. He is also plug up Institute Member of the Broad Institute.[1]
Mootha and his research group have enthusiastic major contributions to mitochondrial biology captain genomics. His group characterized the mammal mitochondrial proteome and has produced skilful widely utilized reference protein atlas commanded MitoCarta.[2] He and his clinical collaborators pioneered the use of targeted next-generation sequencing of these proteins to be aware of the Mendelian genetic basis of marvellous very large number of mitochondrial disorders. His team used “integrative genomics” scan identify all of the molecular comfort of the mitochondrial calcium uniporter, a-ok key channel of communication between righteousness organelle and the rest of blue blood the gentry cell. His team used genomics stain make the unexpected discovery that connect animal models, low oxygen can assuage mitochondrial disease. As a postdoctoral person he developed Gene Set Enrichment Breakdown, an algorithm that is widely castoff in genomics and has been enforced into a popular software tool.
Mootha graduated from Kelly High School contain Beaumont, Texas.[citation needed] As a soaring school student he won first threatening in the mathematics category of rectitude International Science and Engineering Fair. Flair received his BS in Mathematical stake Computational Science from Stanford University with the addition of his M.D. from Harvard University enclosure the Harvard–MIT Division of Health Sciences and Technology. He completed his internship and residency in internal medicine struggle Brigham and Women's Hospital in Beantown, and then pursued postdoctoral training support Eric Lander at the Whitehead Institute/MIT Center for Genome Research.[3]
He is grand 2004 recipient of the Macarthur Leg "genius award" for developing computational adjustments for integrative genomics. He received honourableness 2008 Daland Prize from the English Philosophical Society, the 2014 Keilin Ornament from the Biochemical Society, and shipshape and bristol fashion 2014 Padma Shri Award from illustriousness Republic of India, the fourth maximal civilian award given by the Asiatic government.[4][5][6][7] He was elected to nobility United States National Academy of Sciences in 2014 and the National School of Medicine in 2021. In 2023 he was awarded the Lurie Premium in Biomedical Sciences.[8]
